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KMID : 0384320070280060460
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Korean Journal of Family Medicine
2007 Volume.28 No. 6 p.460 ~ p.465
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A Case Report of Amiodarone-induced Multiple Toxicity after a Long Course of a Low Dose Therapy
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Ryu Dong-Hwan
Park Jae-Hyeok
Hwang Hwan-Sik
Park Hoon-Ki
Jeon Seok-Chol
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Abstract
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Amiodarone is a potent antiarrhythmic agent that is used to treat ventricular arrhythmias and atrial fibrillation. But it has a wide range of adverse effects, including pulmonary toxicity, thyroid dysfunction, liver toxicity, gastrointestinal events, corneal deposits, peripheral neuropathy and so on. Patients treated with amiodarone should be followed regularly to assess ongoing need for amiodarone, efficacy of the drug, appropriateness of dosage, adverse effects, and potential drug interactions. We experienced a case of severe weight loss due to amiodarone-induced multiple toxicity after a long course of a low dose therapy. So we report this unusual case with literature review. (J Korean Acad Fam Med 2007;28: 460-465)
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KEYWORD
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amiodarone, adverse effects, pulmonary toxicity, thyrotoxicosis, anorexia, weight loss
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